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Unexpected linear ion trap collision-induced dissociation and Fourier transform ion cyclotron resonance infrared multi-photon dissociation fragmentation of a hydrated C-glycoside of 5-fluorouridine formed by the action of the pseudouridine synthases RluA and TruB

As part of the investigation of the pseudouridine synthases, 5-fluorouridine in RNA was employed as a mechanistic probe. The hydrated, rearranged product of 5-fluorouridine was isolated as part of a dinucleotide and found to undergo unusual fragmentation during mass spectrometry, with the facile los...

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Bibliografiset tiedot
Julkaisussa:Rapid Commun Mass Spectrom
Päätekijät: Miracco, Edward J., Bogdanov, Bogdan, Mueller, Eugene G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728650/
https://ncbi.nlm.nih.gov/pubmed/23657957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.5162
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