Mechanistic Investigations of the Pseudouridine Synthase RluA using RNA containing 5-Fluorouridine

The pseuoduridine synthases (Ψ synthases) isomerize uridine (U) to pseudouridine (Ψ) in RNA, and they fall into five families that share very limited sequence similarity but have the same overall fold and active site architecture, including an essential Asp. The mechanism by which the Ψ synthases op...

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Bibliografiska uppgifter
Huvudupphovsmän: Hamilton, Christopher S., Greco, Todd M., Vizthum, Caroline A., Ginter, Joy M., Johnston, Murray V., Mueller, Eugene G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580076/
https://ncbi.nlm.nih.gov/pubmed/17002302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061293x
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