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Mechanistic Investigations of the Pseudouridine Synthase RluA using RNA containing 5-Fluorouridine

The pseuoduridine synthases (Ψ synthases) isomerize uridine (U) to pseudouridine (Ψ) in RNA, and they fall into five families that share very limited sequence similarity but have the same overall fold and active site architecture, including an essential Asp. The mechanism by which the Ψ synthases op...

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書誌詳細
主要な著者: Hamilton, Christopher S., Greco, Todd M., Vizthum, Caroline A., Ginter, Joy M., Johnston, Murray V., Mueller, Eugene G.
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580076/
https://ncbi.nlm.nih.gov/pubmed/17002302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061293x
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