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Not all pseudouridine synthases are potently inhibited by RNA containing 5-fluorouridine

RNA containing 5-fluorouridine has been assumed to inhibit strongly or irreversibly the pseudouridine synthases that act on the RNA. RNA transcripts containing 5-fluorouridine in place of uridine have, therefore, been added to reconstituted systems in order to investigate the importance of particula...

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Detalhes bibliográficos
Main Authors: SPEDALIERE, CHRISTOPHER J., MUELLER, EUGENE G.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by RNA Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370531/
https://ncbi.nlm.nih.gov/pubmed/14730018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5100104
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