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The Pseudouridine Synthases Proceed through a Glycal Intermediate
[Image: see text] The pseudouridine synthases isomerize (U) in RNA to pseudouridine (Ψ), and the mechanism that they follow has long been a question of interest. The recent elucidation of a product of the mechanistic probe 5-fluorouridine that had been epimerized to the arabino isomer suggested that...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2016
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4929527/ https://ncbi.nlm.nih.gov/pubmed/27292228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b04491 |
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