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Preferential expression of the novel alternative isoform I.3 of Hypoxia-Inducible Factor 1α in activated human T lymphocytes

Hypoxia-Inducible Factor 1α (HIF-1α) is critical not only in the regulation of oxygen homeostasis, but also in the regulation of innate and adaptive immune systems. We previously reported that TCR-mediated activation of T cells in mice leads to the expression of an alternative isoform of HIF-1α that...

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Autori principali: Lukashev, Dmitriy, Sitkovsky, Michail
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577919/
https://ncbi.nlm.nih.gov/pubmed/18638657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2008.05.004
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