Toll-like Receptor 3 Regulates Angiogenesis and Apoptosis in Prostate Cancer Cell Lines through Hypoxia-Inducible Factor 1α

Toll-like receptors (TLRs) recognize microbial/viral-derived components that trigger innate immune response and conflicting data implicate TLR agonists in cancer, either as protumor or antitumor agents. We previously demonstrated that TLR3 activation mediated by its agonist poly(I:C) induces antitum...

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Hauptverfasser: Paone, Alessio, Galli, Roberta, Gabellini, Chiara, Lukashev, Dmitriy, Starace, Donatella, Gorlach, Agnes, De Cesaris, Paola, Ziparo, Elio, Del Bufalo, Donatella, Sitkovsky, Michail V, Filippini, Antonio, Riccioli, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907580/
https://ncbi.nlm.nih.gov/pubmed/20651983
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