TLR3 engagement induces IRF-3-dependent apoptosis in androgen-sensitive prostate cancer cells and inhibits tumour growth in vivo

Toll-like receptors (TLRs) are a family of highly conserved transmembrane proteins expressed in epithelial and immune cells that recognize pathogen associated molecular patterns. Besides their role in immune response against infections, numerous studies have shown an important role of different TLRs...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Gambara, Guido, Desideri, Marianna, Stoppacciaro, Antonella, Padula, Fabrizio, De Cesaris, Paola, Starace, Donatella, Tubaro, Andrea, del Bufalo, Donatella, Filippini, Antonio, Ziparo, Elio, Riccioli, Anna
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407608/
https://ncbi.nlm.nih.gov/pubmed/25444175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12379
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