Toll-like receptor 3 (TLR3) activation induces microRNA-dependent reexpression of functional RARβ and tumor regression

Toll-like receptor 3 (TLR3) is a key effector of the innate immune system against viruses. Activation of TLR3 exerts an antitumoral effect through a mechanism of action still poorly understood. Here we show that TLR3 activation by polyinosinic:polycytidylic acid induces up-regulation of microRNA-29b...

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Bibliografiset tiedot
Päätekijät: Galli, Roberta, Paone, Alessio, Fabbri, Muller, Zanesi, Nicola, Calore, Federica, Cascione, Luciano, Acunzo, Mario, Stoppacciaro, Antonella, Tubaro, Andrea, Lovat, Francesca, Gasparini, Pierluigi, Fadda, Paolo, Alder, Hansjuerg, Volinia, Stefano, Filippini, Antonio, Ziparo, Elio, Riccioli, Anna, Croce, Carlo M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2013
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683754/
https://ncbi.nlm.nih.gov/pubmed/23716670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304610110
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