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Transfected Poly(I:C) Activates Different dsRNA Receptors, Leading to Apoptosis or Immunoadjuvant Response in Androgen-independent Prostate Cancer Cells

Despite the effectiveness of surgery or radiation therapy for the treatment of early-stage prostate cancer (PCa), there is currently no effective strategy for late-stage disease. New therapeutic targets are emerging; in particular, dsRNA receptors Toll-like receptor 3 (TLR3) and cytosolic helicases...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Palchetti, Sara, Starace, Donatella, De Cesaris, Paola, Filippini, Antonio, Ziparo, Elio, Riccioli, Anna
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342463/
https://ncbi.nlm.nih.gov/pubmed/25568326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.601625
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