TLR3 engagement induces IRF-3-dependent apoptosis in androgen-sensitive prostate cancer cells and inhibits tumour growth in vivo

Toll-like receptors (TLRs) are a family of highly conserved transmembrane proteins expressed in epithelial and immune cells that recognize pathogen associated molecular patterns. Besides their role in immune response against infections, numerous studies have shown an important role of different TLRs...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Gambara, Guido, Desideri, Marianna, Stoppacciaro, Antonella, Padula, Fabrizio, De Cesaris, Paola, Starace, Donatella, Tubaro, Andrea, del Bufalo, Donatella, Filippini, Antonio, Ziparo, Elio, Riccioli, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407608/
https://ncbi.nlm.nih.gov/pubmed/25444175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12379
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