Caricamento...
Identification of an Alternative Mechanism of Degradation of the Hypoxia-inducible Factor-1α
The hypoxia-inducible factor-1α (HIF-1α) is a master regulator of the cellular response to decreased oxygen levels. This transcription factor is highly unstable at normal oxygen concentrations and is rapidly stabilized by hypoxia. At normoxia two specific proline residues (Pro(402) and Pro(563)) of...
Salvato in:
| Autori principali: | , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2008
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662024/ https://ncbi.nlm.nih.gov/pubmed/18694926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805919200 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|