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Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1α-deficient chimeric mice

Immune cells are exposed to low oxygen tensions as they develop and migrate between blood and different tissues, but the mechanisms by which lymphocytes adapt to hypoxia are poorly understood. Studies reported here of hypoxia-inducible factor 1α (HIF-1α) in lymphocyte development and functions sugge...

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Bibliografiska uppgifter
Huvudupphovsmän: Kojima, Hidefumi, Gu, Hua, Nomura, Saeko, Caldwell, Charles C., Kobata, Tetsuji, Carmeliet, Peter, Semenza, Gregg L., Sitkovsky, Michail V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2002
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC122337/
https://ncbi.nlm.nih.gov/pubmed/11854513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052706699
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