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Chronic intrauterine pulmonary hypertension increases endothelial cell Rho kinase activity and impairs angiogenesis in vitro

Persistent pulmonary hypertension of the newborn (PPHN) is characterized by endothelial dysfunction and decreased vascular growth. The role of Rho kinase activity in modulating endothelial function and regulating angiogenesis during normal lung development and in PPHN is unknown. We hypothesized tha...

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書誌詳細
主要な著者: Gien, Jason, Seedorf, Gregory J., Balasubramaniam, Vivek, Tseng, Nancy, Markham, Neil, Abman, Steven H.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575951/
https://ncbi.nlm.nih.gov/pubmed/18621906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00516.2007
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