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Segregation and activation of myosin IIB creates a rear in migrating cells

We have found that MLC-dependent activation of myosin IIB in migrating cells is required to form an extended rear, which coincides with increased directional migration. Activated myosin IIB localizes prominently at the cell rear and produces large, stable actin filament bundles and adhesions, which...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Vicente-Manzanares, Miguel, Koach, Margaret A., Whitmore, Leanna, Lamers, Marcelo L., Horwitz, Alan F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575793/
https://ncbi.nlm.nih.gov/pubmed/18955554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200806030
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