Загрузка...
Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3
INTRODUCTION: ErbB2, a member of the epidermal growth factor receptor (EGFR) family, is overexpressed in 20% to 30% of human breast cancer cases and forms oncogenic signalling complexes when dimerised to ErbB3 or other EGFR family members. METHODS: We crossed mouse mammary tumour virus (MMTV)-myr-Ak...
Сохранить в:
| Главные авторы: | , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2008
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575543/ https://ncbi.nlm.nih.gov/pubmed/18700973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2132 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|