Caloric restriction inhibits mammary tumorigenesis in MMTV-ErbB2 transgenic mice through the suppression of ER and ErbB2 pathways and inhibition of epithelial cell stemness in premalignant mammary tissues

Caloric intake influences the onset of many diseases, including cancer. In particular, caloric restriction (CR) has been reported to suppress mammary tumorigenesis in various models. However, the underlying cancer preventive mechanisms have not been fully explored. To this end, we aimed to character...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Carcinogenesis
Prif Awduron: Ma, Zhikun, Parris, Amanda B, Howard, Erin W, Shi, Yujie, Yang, Shihe, Jiang, Yunbo, Kong, Lingfei, Yang, Xiaohe
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Inflammation, Microenvironment and Prevention
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175030/
https://ncbi.nlm.nih.gov/pubmed/30107476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgy096
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