Short-term early exposure to lapatinib confers lifelong protection from mammary tumor development in MMTV-erbB-2 transgenic mice

BACKGROUND: Although chemopreventative agents targeting the estrogen/estrogen receptor (ER) pathway have been effective for ER(+) breast cancers, prevention of hormone receptor-negative breast cancers, such as Her2/erbB-2(+) breast cancers, remains a significant issue. Previous studies have demonstr...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Ma, Zhikun, Parris, Amanda B., Xiao, Zhengzheng, Howard, Erin W., Kosanke, Stanley D., Feng, Xiaoshan, Yang, Xiaohe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217213/
https://ncbi.nlm.nih.gov/pubmed/28061785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0479-8
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