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Gemini Vitamin D Analog Suppresses ErbB2-Positive Mammary Tumor Growth via Inhibition of ErbB2/AKT/ERK Signaling

Numerous synthetic vitamin D analogs have been studied for their effects on the prevention and treatment of breast cancer. However, the inhibitory effects of naturally occurring 1α,25-dihydroxyvitamin D(3) or its synthetic analogs on ErbB2 overexpressing mammary tumorigenesis have not been reported....

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Détails bibliographiques
Auteurs principaux: Lee, Hong Jin, So, Jae-Young, DeCastro, Andrew, Smolarek, Amanda, Paul, Shiby, Maehr, Hubert, Uskokovic, Milan, Suh, Nanjoo
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906695/
https://ncbi.nlm.nih.gov/pubmed/20304052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2010.03.053
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