Oral administration of a Gemini vitamin D analog, a synthetic triterpenoid and the combination prevents mammary tumorigenesis driven by ErbB2 overexpression

Human epidermal growth factor receptor 2 (HER2 or ErbB2), a member of ErbB receptor tyrosine kinases, is overexpressed in approximately 20 % of human breast cancer, and the ErbB2 signaling pathway is a critical therapeutic target for ErbB2-overexpressing breast cancer. We investigated the inhibitory...

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Detalhes bibliográficos
Main Authors: So, Jae Young, Wahler, Joseph E., Yoon, Taesook, Smolarek, Amanda K., Lin, Yong, Shih, Weichung Joe, Maehr, Hubert, Uskokovic, Milan, Liby, Karen T., Sporn, Michael B., Suh, Nanjoo
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767182/
https://ncbi.nlm.nih.gov/pubmed/23856074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0087
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