Targeting CD44-STAT3 Signaling by Gemini Vitamin D Analog Leads to Inhibition of Invasion in Basal-Like Breast Cancer

BACKGROUND: CD44, a transmembrane glycoprotein, is a major receptor for extracellular proteins involved in invasion and metastasis of human cancers. We have previously demonstrated that the novel Gemini vitamin D analog BXL0124 [1α,25-dihydroxy-20R-21(3-hydroxy-3-deuteromethyl-4,4,4-trideuterobutyl)...

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Detalhes bibliográficos
Main Authors: So, Jae Young, Smolarek, Amanda K., Salerno, David M., Maehr, Hubert, Uskokovic, Milan, Liu, Fang, Suh, Nanjoo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543376/
https://ncbi.nlm.nih.gov/pubmed/23326564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054020
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