HES1-mediated inhibition of Notch1 signaling by a Gemini vitamin D analog leads to decreased CD44(+)/CD24(−/low) tumor-initiating subpopulation in basal-like breast cancer

Tumor-initiating cells (also known as cancer stem cells) are the subpopulation of cells shown to be responsible for tumor initiation, maintenance and recurrence. In breast cancer, CD44(+)/CD24(−/low) cells were identified as tumor-initiating cells. We previously reported that a Gemini vitamin D anal...

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Détails bibliographiques
Publié dans:J Steroid Biochem Mol Biol
Auteurs principaux: So, Jae Young, Wahler, Joseph, Gupta, Soumyasri Das, Salerno, David M., Maehr, Hubert, Uskokovic, Milan, Suh, Nanjoo
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361253/
https://ncbi.nlm.nih.gov/pubmed/25541438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2014.12.013
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