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HES1-mediated inhibition of Notch1 signaling by a Gemini vitamin D analog leads to decreased CD44(+)/CD24(−/low) tumor-initiating subpopulation in basal-like breast cancer
Tumor-initiating cells (also known as cancer stem cells) are the subpopulation of cells shown to be responsible for tumor initiation, maintenance and recurrence. In breast cancer, CD44(+)/CD24(−/low) cells were identified as tumor-initiating cells. We previously reported that a Gemini vitamin D anal...
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| Veröffentlicht in: | J Steroid Biochem Mol Biol |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4361253/ https://ncbi.nlm.nih.gov/pubmed/25541438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2014.12.013 |
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