A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice

Overexpression of the NEDD9/HEF1/Cas-L scaffolding protein is frequent, and drives invasion and metastasis in breast, head and neck, colorectal, melanoma, lung, and other types of cancer. We have examined the consequences of genetic ablation of Nedd9 in the MMTV-HER2/ERBB2/neu mouse mammary tumor mo...

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Hauptverfasser: Little, Joy L., Serzhanova, Victoria, Izumchenko, Eugene, Egleston, Brian L., Parise, Erica, Klein-Szanto, Andres J., Loudon, Grace, Shubina, Maria, Seo, Sachiko, Kurokawa, Mineo, Ochs, Michael F., Golemis, Erica A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628996/
https://ncbi.nlm.nih.gov/pubmed/23318423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.607
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