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Enhanced genetic instability and dasatinib sensitivity in mammary tumor cells lacking Nedd9
Elevated expression of the Nedd9/HEF1/Cas-L scaffolding protein promotes tumor cell invasion and metastasis in multiple cancer cell types. Conversely, generation of mammary tumors in the MMTV-polyoma virus middle T (PyVT) genetic model is delayed by a Nedd9(−/−) genotype. These activities arise from...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970659/ https://ncbi.nlm.nih.gov/pubmed/20940402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0353 |
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