טוען...
Nedd9 restrains renal cystogenesis in Pkd1(−/−) mice
Mutations inactivating the cilia-localized Pkd1 protein result in autosomal dominant polycystic kidney disease (ADPKD), a serious inherited syndrome affecting ∼1 in 500 people, in which accumulation of renal cysts eventually destroys kidney function. Severity of ADPKD varies throughout the populatio...
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Main Authors: | , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
National Academy of Sciences
2014
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156736/ https://ncbi.nlm.nih.gov/pubmed/25139996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405362111 |
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