Nedd9 restrains renal cystogenesis in Pkd1(−/−) mice

Mutations inactivating the cilia-localized Pkd1 protein result in autosomal dominant polycystic kidney disease (ADPKD), a serious inherited syndrome affecting ∼1 in 500 people, in which accumulation of renal cysts eventually destroys kidney function. Severity of ADPKD varies throughout the populatio...

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Bibliographic Details
Main Authors: Nikonova, Anna S., Plotnikova, Olga V., Serzhanova, Victoria, Efimov, Andrey, Bogush, Igor, Cai, Kathy Q., Hensley, Harvey H., Egleston, Brian L., Klein-Szanto, Andres, Seeger-Nukpezah, Tamina, Golemis, Erica A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156736/
https://ncbi.nlm.nih.gov/pubmed/25139996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405362111
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