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ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini
Both ErbB1 and ErbB2 are overexpressed or amplified in breast tumours. To examine the effects of activating ErbB receptors in a context that mimics polarized epithelial cells in vivo, we activated ErbB1 and ErbB2 homodimers in preformed, growth-arrested mammary acini cultured in three-dimensional ba...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952547/ https://ncbi.nlm.nih.gov/pubmed/11533657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb0901-785 |
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