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Brk is coamplified with ErbB2 to promote proliferation in breast cancer
Amplification of the receptor tyrosine kinase ErbB2 is frequently observed in breast cancer. Amplification of erbB2 is also associated with multiple genomic gains and losses; however, the importance of these associated changes is largely unknown. We demonstrate that Brk, a cytoplasmic tyrosine kinas...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527934/ https://ncbi.nlm.nih.gov/pubmed/18719096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805009105 |
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