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Proliferation of Colorectal Cancer Is Promoted by Two Signaling Transduction Expression Patterns: ErbB2/ErbB3/AKT and MET/ErbB3/MAPK

One of the recent breakthroughs in cancer research is the identification of activating mutations in various receptor tyrosine kinase(RTK) pathways in many cancers including colorectal cancer(CRC). We hypothesize that, alternative to mutations, overexpression of various oncogenic RTKs may also underp...

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Detalhes bibliográficos
Main Authors: Yao, Yong-Liang, Shao, Jie, Zhang, Chunfu, Wu, Jian-Hong, Zhang, Qing-Hui, Wang, Jian-Jun, Zhu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813539/
https://ncbi.nlm.nih.gov/pubmed/24205104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078086
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