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Late sodium current is a new therapeutic target to improve contractility and rhythm in failing heart

Most cardiac Na(+) channels open transiently within milliseconds upon membrane depolarization and are responsible for the excitation propagation. However, some channels remain active during hundreds of milliseconds, carrying the so-called persistent or late Na(+) current (I(NaL)) throughout the acti...

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Autors principals: Undrovinas, Albertas, Maltsev, Victor A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575131/
https://ncbi.nlm.nih.gov/pubmed/18855648
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