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Late sodium current is a new therapeutic target to improve contractility and rhythm in failing heart
Most cardiac Na(+) channels open transiently within milliseconds upon membrane depolarization and are responsible for the excitation propagation. However, some channels remain active during hundreds of milliseconds, carrying the so-called persistent or late Na(+) current (I(NaL)) throughout the acti...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575131/ https://ncbi.nlm.nih.gov/pubmed/18855648 |
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