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Late sodium current in failing heart: Friend or foe?

Most cardiac Na(+) channels open transiently upon membrane depolarization and then are quickly inactivated. However, some channels remain active, carrying the so-called persistent or late Na(+) current (I(NaL)) throughout the action potential (AP) plateau. Experimental data and the results of numeri...

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Détails bibliographiques
Auteurs principaux: Maltsev, Victor A., Undrovinas, Albertas
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267741/
https://ncbi.nlm.nih.gov/pubmed/17854868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2007.07.010
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