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Contribution of sodium channel neuronal isoform Na(v)1.1 to late sodium current in ventricular myocytes from failing hearts
Late Na(+) current (I(NaL)) contributes to action potential (AP) duration and Ca(2+) handling in cardiac cells. Augmented I(NaL) was implicated in delayed repolarization and impaired Ca(2+) handling in heart failure (HF). We tested if Na(+) channel (Na(v)) neuronal isoforms contribute to I(NaL) and...
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| Veröffentlicht in: | J Physiol |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376421/ https://ncbi.nlm.nih.gov/pubmed/25772296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.278259 |
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