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Late sodium current is a new therapeutic target to improve contractility and rhythm in failing heart
Most cardiac Na(+) channels open transiently within milliseconds upon membrane depolarization and are responsible for the excitation propagation. However, some channels remain active during hundreds of milliseconds, carrying the so-called persistent or late Na(+) current (I(NaL)) throughout the acti...
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| Главные авторы: | , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575131/ https://ncbi.nlm.nih.gov/pubmed/18855648 |
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