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Positive Modulation of GABA(B) Receptors Decreased Nicotine Self-administration and Counteracted Nicotine-induced Enhancement of Brain Reward Function in Rats
Acute administration of γ-aminobutyric acid (GABA)-B receptor agonists decreases nicotine, cocaine, ethanol, and heroin self-administration, and also decreases food-maintained responding and suppresses locomotor activity at high doses. GABA(B) receptor positive modulators may represent potentially i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574924/ https://ncbi.nlm.nih.gov/pubmed/18445779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.139204 |
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