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Conditioned Nicotine Withdrawal Profoundly Decreases the Activity of Brain Reward Systems

Withdrawal from nicotine decreases the activity of brain reward systems, measured in rats by elevations of intracranial self-stimulation (ICSS) thresholds. This reward deficit is hypothesized to contribute to the persistence of the tobacco habit in tobacco smokers. Accumulating evidence suggests tha...

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Pubblicato in:J Neurosci
Autori principali: Kenny, Paul J., Markou, Athina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725046/
https://ncbi.nlm.nih.gov/pubmed/15987950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4785-04.2005
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