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Involvement of metabotropic glutamate receptor 5 in brain reward deficits of cocaine and nicotine withdrawal, and somatic signs of nicotine withdrawal

RATIONALE: Involvement of metabotropic glutamate 5 (mGlu5) receptors has been suggested in the reinforcing effects of psychostimulants. However, little is known about the role of these receptors in psychostimulant withdrawal. OBJECTIVES: The role of mGlu5 receptors was assessed in the anhedonic and...

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Главные авторы: Stoker, Astrid K., Olivier, Berend, Markou, Athina
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010095/
https://ncbi.nlm.nih.gov/pubmed/22147259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2578-8
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