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The effects of chronic versus acute desipramine on nicotine withdrawal and nicotine self-administration in the rat

RATIONALE: Nicotine withdrawal is characterized by depression-like symptomatology that may be mediated by dysregulations in norepinephrine transmission. These aversive aspects of nicotine withdrawal and the rewarding effects of nicotine play major roles in maintaining nicotine dependence. OBJECTIVES...

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Detalhes bibliográficos
Main Authors: Paterson, Neil E., Semenova, Svetlana, Markou, Athina
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2452988/
https://ncbi.nlm.nih.gov/pubmed/18438738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-008-1144-5
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