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In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-β1
Transforming growth factor-β1 (TGF-β1) has potent physiologic and pathologic effects on a variety of cell types at subnanomolar concentrations. Platelets contain 40 times as much TGF-β1 as other cells and secrete it as an inactive (latent) form in complex with latency-associated peptide (LAP), which...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society of Hematology
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572792/ https://ncbi.nlm.nih.gov/pubmed/18544680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-151753 |
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