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Association Between Shear Stress and Platelet-derived TGF-β1 Release and Activation in Animal Models of Aortic Valve Stenosis
OBJECTIVE: Aortic valve stenosis (AS) is characterized by fibrosis and calcification of valves leading to aortic valve (AV) narrowing, resulting in high wall shear stress (WSS) across the valves. We previously demonstrated that high shear stress can activate platelet-derived transforming growth fact...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4141006/ https://ncbi.nlm.nih.gov/pubmed/24903096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.303852 |
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