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Stress and IGF-I Differentially Control Cell Fate through Mammalian Target of Rapamycin (mTOR) and Retinoblastoma Protein (pRB)

Significant discoveries have recently contributed to our knowledge of intracellular growth factor and nutrient signaling via mTOR (mammalian target of rapamycin). This signaling pathway is essential in cellular metabolism and cell survival by enhancing protein translation through phosphorylation of...

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Detalhes bibliográficos
Main Authors: Popowski, Melissa, Ferguson, Heather A., Sion, Amy M., Koller, Erich, Knudsen, Erik, Van Den Berg, Carla L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568931/
https://ncbi.nlm.nih.gov/pubmed/18697743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805724200
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