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Three Metal Ions Participate in the Reaction Catalyzed by T5 Flap Endonuclease

Protein nucleases and RNA enzymes depend on divalent metal ions to catalyze the rapid hydrolysis of phosphate diester linkages of nucleic acids during DNA replication, DNA repair, RNA processing, and RNA degradation. These enzymes are widely proposed to catalyze phosphate diester hydrolysis using a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Syson, Karl, Tomlinson, Christopher, Chapados, Brian R., Sayers, Jon R., Tainer, John A., Williams, Nicholas H., Grasby, Jane A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568906/
https://ncbi.nlm.nih.gov/pubmed/18697748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801264200
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