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Human Flap Endonuclease I Is in Complex with Telomerase and Is Required for Telomerase-mediated Telomere Maintenance

Studies from budding yeast and ciliates have suggested that telomerase extension of telomeres requires the conventional DNA replication machinery, yet little is known about how DNA replication proteins regulate telomerase action in higher eukaryotic cells. Here we investigate the role of one of the...

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Библиографические подробности
Главные авторы: Sampathi, Shilpa, Bhusari, Amruta, Shen, Binghui, Chai, Weihang
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635043/
https://ncbi.nlm.nih.gov/pubmed/19068479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805362200
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