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Molecular steps of G-overhang generation at human telomeres and its function in chromosome end protection
Telomeric G-overhangs are required for the formation of the protective telomere structure and telomerase action. However, the mechanism controlling G-overhang generation at human telomeres is poorly understood. Here, we show that G-overhangs can undergo cell cycle-regulated changes independent of te...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924643/ https://ncbi.nlm.nih.gov/pubmed/20639858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.156 |
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