Molecular steps of G-overhang generation at human telomeres and its function in chromosome end protection

Telomeric G-overhangs are required for the formation of the protective telomere structure and telomerase action. However, the mechanism controlling G-overhang generation at human telomeres is poorly understood. Here, we show that G-overhangs can undergo cell cycle-regulated changes independent of te...

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Detaylı Bibliyografya
Asıl Yazarlar: Dai, Xueyu, Huang, Chenhui, Bhusari, Amruta, Sampathi, Shilpa, Schubert, Kathryn, Chai, Weihang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924643/
https://ncbi.nlm.nih.gov/pubmed/20639858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.156
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