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CDK1 differentially regulates G-overhang generation at leading- and lagging-strand telomeres in telomerase-negative cells in G(2) phase

Human telomeres contain single-stranded 3' G-overhangs that function in telomere end protection and telomerase action. Previously we have demonstrated that multiple steps involving C-strand end resection, telomerase elongation and C-strand fill-in contribute to G-overhang generation in telomera...

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Bibliografski detalji
Glavni autori: Dai, Xueyu, Huang, Chenhui, Chai, Weihang
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442918/
https://ncbi.nlm.nih.gov/pubmed/22871736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21472
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