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Telomerase-dependent generation of 70-nt-long telomeric single-stranded 3′ overhangs in yeast

Telomeres, the chromatin structures at the ends of eukaryotic chromosomes, are essential for chromosome stability. The telomere terminates with a TG-rich 3′ overhang, which is bound by sequence-specific proteins that both protect the end and regulate the telomerase elongation process. Here, we demon...

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Detalhes bibliográficos
Main Authors: Fridholm, Helena, Astromskas, Eimantas, Cohn, Marita
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592436/
https://ncbi.nlm.nih.gov/pubmed/23125369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1028
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