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Full length RTEL1 is required for the elongation of the single-stranded telomeric overhang by telomerase
Telomeres cap the ends of eukaryotic chromosomes and distinguish them from broken DNA ends to suppress DNA damage response, cell cycle arrest and genomic instability. Telomeres are elongated by telomerase to compensate for incomplete replication and nuclease degradation and to extend the proliferati...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7367169/ https://ncbi.nlm.nih.gov/pubmed/32542379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa503 |
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