लोड हो रहा है...

NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

Egress of lipoprotein-derived cholesterol from lysosomes requires two lysosomal proteins, polytopic membrane-bound Niemann–Pick C1 (NPC1) and soluble Niemann–Pick C2 (NPC2). The reason for this dual requirement is unknown. Previously, we showed that the soluble luminal N-terminal domain (NTD) of NPC...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Infante, Rodney E., Wang, Michael L., Radhakrishnan, Arun, Kwon, Hyock Joo, Brown, Michael S., Goldstein, Joseph L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563079/
https://ncbi.nlm.nih.gov/pubmed/18772377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807328105
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!