Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation

Neural precursor cells (NPCs) differentiate into neurons, astrocytes, and oligodendrocytes in response to intrinsic and extrinsic changes. Notch signals maintain undifferentiated NPCs, but the mechanisms underlying the neuronal differentiation are largely unknown. We show that SIRT1, an NAD(+)-depen...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Hisahara, Shin, Chiba, Susumu, Matsumoto, Hiroyuki, Tanno, Masaya, Yagi, Hideshi, Shimohama, Shun, Sato, Makoto, Horio, Yoshiyuki
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2008
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563076/
https://ncbi.nlm.nih.gov/pubmed/18829436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800612105
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы