Histone deacetylase 3 promotes RCAN1 stability and nuclear translocation.

Regulator of calcineurin 1 (RCAN1; also referred as DSCR1 or MCIP1) is located in close proximity to a Down syndrome critical region of human chromosome 21. Although RCAN1 is an endogenous inhibitor of calcineurin signaling that controls lymphocyte activation, apoptosis, heart development, skeletal...

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Päätekijät: Kyung Ah Han, Hye Seon Kang, Jee Won Lee, Lang Yoo, Eunju Im, Ahyoung Hong, Yun Ju Lee, Woo Hyun Shin, Kwang Chul Chung
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2014-01-01
Sarja:PLoS ONE
Linkit:http://europepmc.org/articles/PMC4140772?pdf=render
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