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A High-Throughput, Homogeneous, Bioluminescent Assay for Pseudomonas aeruginosa Gyrase Inhibitors and Other DNA Damaging Agents
A homogeneous, sensitive, cellular bioluminescent high throughput screen was developed for inhibitors of gyrase and other DNA damaging agents in Pseudomonas aeruginosa. The screen is based on a Photorhabdus luminescens luciferase operon transcriptional fusion to a promoter that responds to DNA damag...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2561246/ https://ncbi.nlm.nih.gov/pubmed/17644773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057107304729 |
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